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KMID : 0043319840070010065
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Archives of Pharmacal Research
1984 Volume.7 No. 1 p.65 ~ p.68
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Identfication of N-Acetyl and Hydroxylated N-Acetyltranylcypromine from Tranylcypromine-Dosed Rat Urine
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Kang GI
Chung SY
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Abstract
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Mechanism of the monoamine oxidase inhibition by tranylcypromine was studied in relation to its metabolism to reactive species. A metabolic study performed to collect general biotransformation pathway in rats provided GC/MS evidence for the detection of two new metabolites, N-acetyl and hydroxylated N-acetyltranylcypromine.
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